Drug Discovery

We offer support ranging from Medicinal Drug Discovery, Library synthesis and synthetic chemistry for critical molecule, to custom synthesis of New chemical entities (NCEs). Furthermore, we offer preparation of NCE intermediates, scaffolds and reference standard and chemical development of clinical drug candidates.

Medicinal Drug discovery

  • Hit Identification
  • Hit-to-lead evaluation
  • Lead optimization
  • Backup series synthesis to de-risking (bioavailability& toxicity) through fast follower approach
  • Contract medicinal chemistry services from Hit identification up to pre-clinical candidates nomination
  • Impurity and metabolic profiling of pre-clinical and clinical drug candidates

Library synthesis and synthetic chemistry

  • External center of medicinal and synthetic chemistry research in drug discovery and development with strategic partnerships in common critical disease areas as well as infectious and neglected transmitted disease (NTD) with a commitment to share knowledge, expertise, ideas, and experience which is crucial in developing the therapies that will be the most beneficial.
  • Co-development of NCEs through Open-Source Drug Discovery (OSDD) especially in neglected diseases and other diseases.
  • We pursue with client and collaborator multiple lines of investigation (In-Vitro & properties assays and In-Vivo studies) with diverse variables and ensembles to integrate the data for the balance of pharmacological activities with efficacy and drug-like properties in the clinical drug candidates.

Custom synthesis

  • Custom-focused and diversified library drug-like compound design and synthesis
  • Custom-focused and diversified building block and scaffolds design and synthesis
  • Reference compound synthesis and scale-up (literature or competitor)
  • Complex molecules and intermediates – synthesis and scale-up
  • Synthesis of pro-drugs and it’s new chemical entities(NCEs)
  • Custom synthesis of patent courage molecule